Sequential recommendation aims to recommend the next item that matches a user's

Deep neural networks, including Convolutional Neural Networks (CNNs) and Visual Transformers (ViT), have achieved stunning success in the medical image domain. We study thorax disease classification in this paper. Effective extraction of features for the disease areas is crucial for disease classification on radiographic images. While various neural architectures and training techniques, such as self-supervised learning with contrastive/restorative learning, have been employed for disease classification on radiographic images, there are no principled methods that can effectively reduce the adverse effect of noise and background or non-disease areas on the radiographic images for disease classification. To address this challenge, we propose a novel Low-Rank Feature Learning (LRFL) method in this paper, which is universally applicable to the training of all neural networks. The LRFL method is both empirically motivated by a Low Frequency Property (LFP) and theoretically motivated by our sharp generalization bound for neural networks with low-rank features. LFP not only widely exists in deep neural networks for generic machine learning but also exists in all the thorax medical datasets studied in this paper. In the empirical study, using a neural network such as a ViT or a CNN pre-trained on unlabeled chest X-rays by Masked Autoencoders (MAE), our novel LRFL method is applied on the pre-trained neural network and demonstrates better classification results in terms of both multi-class area under the receiver operating curve (mAUC) and classification accuracy than the current state-of-the-art.

Training agents that can coordinate zero-shot with humans is a key mission in multi-agent reinforcement learning (MARL). Current algorithms focus on training simulated human partner policies which are then used to train a Cooperator agent. The simulated human is produced either through behavior cloning over a dataset of human cooperation behavior, or by using MARL to create a population of simulated agents. However, these approaches often struggle to produce a Cooperator that can coordinate well with real humans, since the simulated humans fail to cover the diverse strategies and styles employed by people in the real world. We show \emph{learning a generative model of human partners} can effectively address this issue.

Non-interactive cryptographic computing, Fully Homomorphic Encryption (FHE), provides a promising solution for private neural network training on encrypted data. One challenge of FHE-based private training is its large computational overhead, especially the multiple rounds of forward and backward execution on each encrypted data sample. Considering the existence of largely redundant data samples, pruning them will significantly speed up the training, as proven in plain non-FHE training. Executing the data pruning of encrypted data on the server side is not trivial since the knowledge calculation of data pruning needs complex and expensive executions on encrypted data. There is a lack of FHE-based data pruning protocol for efficient, private training. In this paper, we propose, \textit{HEPrune}, to construct a FHE data-pruning protocol and then design an FHE-friendly data-pruning algorithm under client-aided or non-client-aided settings, respectively. We also observed that data sample pruning may not always remove ciphertexts, leaving large empty slots and limiting the effects of data pruning. Thus, in HEPrune, we further propose ciphertext-wise pruning to reduce ciphertext computation numbers without hurting accuracy. Experimental results show that our work can achieve a $16\times$ speedup with only a $0.6\%$ accuracy drop over prior work.

Transformer models have gained significant attention due to their power in machine learning tasks. Their extensive deployment has raised concerns about the potential leakage of sensitive information during inference. However, when being applied to Transformers, existing approaches based on secure two-party computation (2PC) bring about efficiency limitations in two folds: (1) resource-intensive matrix multiplications in linear layers, and (2) complex non-linear activation functions like $\mathsf{GELU}$ and $\mathsf{Softmax}$. This work presents a new two-party inference framework $\mathsf{Nimbus}$ for Transformer models. Specifically, we propose a new 2PC paradigm to securely compute matrix multiplications based on an outer-product insight, which achieves $2.9\times \sim 12.5\times$ performance improvements compared to the state-of-the-art (SOTA) protocol. Furthermore, through a new observation of utilizing the input distribution, we propose an approach of low-degree polynomial approximation for $\mathsf{GELU}$ and $\mathsf{Softmax}$, which improves the performance of the SOTA polynomial approximation by $2.9\times \sim 4.0\times$, where the average accuracy loss of our approach is 0.08\% compared to the non-2PC inference without privacy. Compared with the SOTA two-party inference, $\mathsf{Nimbus}$ improves the end-to-end performance of $BERT_{base}$ inference by $2.7\times \sim 4.7\times$ across different network settings.

Large Language Model (LLM) agents are emerging to transform daily life. However, existing LLM agents primarily follow a reactive paradigm, relying on explicit user instructions to initiate services, which increases both physical and cognitive workload. In this paper, we propose ProAgent, the first end-to-end proactive agent system that harnesses massive sensory contexts and LLM reasoning to deliver proactive assistance. ProAgent first employs a proactive-oriented context extraction approach with on-demand tiered perception to continuously sense the environment and derive hierarchical contexts that incorporate both sensory and persona cues. ProAgent then adopts a context-aware proactive reasoner to map these contexts to user needs and tool calls, providing proactive assistance. We implement ProAgent on Augmented Reality (AR) glasses with an edge server and extensively evaluate it on a real-world testbed, a public dataset, and through a user study. Results show that ProAgent achieves up to 33.4% higher proactive prediction accuracy, 16.8% higher tool-calling F1 score, and notable improvements in user satisfaction over state-of-the-art baselines, marking a significant step toward proactive assistants. A video demonstration of ProAgent is available at https://youtu.be/pRXZuzvrcVs.

Large language models (LLMs) are increasingly being applied to clinical care, a domain where both accuracy and transparent reasoning are critical for safe and trustworthy deployment. Chain-of-thought (CoT) prompting, which elicits step-by-step reasoning, has demonstrated improvements in performance and interpretability across a wide range of tasks. However, its effectiveness in clinical contexts remains largely unexplored, particularly in the context of electronic health records (EHRs), the primary source of clinical documentation, which are often lengthy, fragmented, and noisy. In this work, we present the first large-scale systematic study of CoT for clinical text understanding. We assess 95 advanced LLMs on 87 real-world clinical text tasks, covering 9 languages and 8 task types. Contrary to prior findings in other domains, we observe that 86.3\% of models suffer consistent performance degradation in the CoT setting. More capable models remain relatively robust, while weaker ones suffer substantial declines. To better characterize these effects, we perform fine-grained analyses of reasoning length, medical concept alignment, and error profiles, leveraging both LLM-as-a-judge evaluation and clinical expert evaluation. Our results uncover systematic patterns in when and why CoT fails in clinical contexts, which highlight a critical paradox: CoT enhances interpretability but may undermine reliability in clinical text tasks. This work provides an empirical basis for clinical reasoning strategies of LLMs, highlighting the need for transparent and trustworthy approaches.

Adversarial learning has been attracting more and more attention thanks to the fast development of machine learning and artificial intelligence. However, due to the complicated structure of most machine learning models, the mechanism of adversarial attacks is not well interpreted. How to measure the effect of attacks is still not quite clear. In this paper, we investigate the adversarial learning from the perturbation analysis point of view. We characterize the robustness of learning models through the calmness of the solution mapping. In the case of convex clustering models, we identify the conditions under which the clustering results remain the same under perturbations. When the noise level is large, it leads to an attack. Therefore, we propose two bilevel models for adversarial learning where the effect of adversarial learning is measured by some deviation function. Specifically, we systematically study the so-called $δ$-measure and show that under certain conditions, it can be used as a deviation function in adversarial learning for convex clustering models. Finally, we conduct numerical tests to verify the above theoretical results as well as the efficiency of the two proposed bilevel models.